City supporters are asked to light torches when the players enter the field in Saturday's visit of Salford City (December 21).
The 3.00pm encounter will aim to make the Utilita Energy Stadium 'Sparkle for Axl'.
Supporting the Sparkle for Axl campaign, the match will also be dedicated to the Bradford Teaching Hospitals NHS Foundation Trust.
Axl was a much-loved patient at Bradford Royal Infirmary and who passed away from a rare blood disorder, last year, three days before his third birthday.
Axl's older brother, Lucas, will appear as a mascot for the Bantams' meeting with the Moor Lane outfit and will walk out with the players to see City's home lit up.
Lucas, a big supporter of Gary Bowyer's side, was invited to the club's Woodhouse Grove training base, last month, to meet with goalkeeper Richard O’Donnell and help launch the appeal.
Claire Walker, Axl’s mum, said: "It means a lot to our family to keep Axl’s memory alive and to raise money to help other children in hospital.
"We would love to see the Sparkle for Axl day become an annual Christmas fundraising event in Bradford, with everyone supporting their local NHS charity and children in their home city."
City's director of communications, Ryan Sparks, said: "We are proud to be working with the Bradford Teaching Hospitals NHS Foundation Trust, as one of our official charity partners for this season.
"As part of this season’s initiative, we are able to support the Sparkle For Axl campaign and the fantastic work the initiative does to help bring festive cheer to youngsters at Christmas.
"We urge supporters to back Sparkle for Axl as much as possible, against Salford, to make the occassion a memorable one for Axl's loved ones."
For more information about the Sparkle for Axl campaign, please CLICK HERE where you can also register your interest in taking part.