The match (kick off 3:00pm) is scheduled to be City's final game of 2015, and it also marks the official start of the 'second half' of the 2015/2016 campaign.
United will be the first side City have faced twice in the league so far this season come Monday, plus this set of fixtures is due to be the 24th in Sky Bet League 1 this year - just over half of the 46 matches each side will play in the regular season.
The Bantams, of course, are a couple of games behind, however, due to recent postponements against Southend United and Burton Albion.
The game will be fourth time Phil Parkinson has took charge of City against the Blades at Bramall Lane after two previous league fixtures and one dramatic Johnstone's Paint Trophy tie won by the Bantams on penalties.
City's most recent encounter with the Blades at Bramall Lane came back in April when Billy Clarke's leveller secured a 1-1 draw. The Bantams also drew 2-2 with United in January 2014.
Clarke is one of four former Sheffield United players currently in City's squad, the other three being Tony McMahon, Kyel Reid and Steven Davies.
In the United camp, shot-stopper Mark Howard had a brief trial period with City under Peter Jackson back in the summer of 2011.
Down the years, there have been a large number of notable players to have played for both clubs in the recent past.
They include legendary former Bantams midfielder Stuart McCall, Bobby Campbell, Dean Windass, Chris Kamara, Andy Gray, Rob Kozluk, Gus Uhlenbeek, Simon Francis, Keith Gillespie, John Egan, Nicky Law, Chris Wilder, Dean Saunders, Mark Yeates, Peter Beagrie, Danny Cadamarteri, Bruce Dyer, Michael Boulding, Richard Edghill, Lee Hendrie, Billy Paynter, Chris O'Grady, Kyle Nix, Marcel Seip and Jon Stead.